Hello. This is my attempt at a semi-professional website describing my research.
My research is aimed at understanding the molecular basis of evolution. The yeast Saccharomyces cerevisiae is an ideal system for studying evolution in the laboratory: yeast is amenable to genetics and genomics studies, and many strains of S. cerevisiae as well as closely related species have been sequenced. These tools allow us to analyze historical events that led to the modern yeast species.
In addition to these case studies in evolution, I am interested in general principles of evolution such as the nature of beneficial and deleterious mutations and how parameters such as mutation rate, the distribution of mutational effects on fitness, and epistasis set the rate of adaptation.
In 2007 I completed my Ph.D. with Andrew Murray at Harvard University where I characterized mutation rate variation in yeast. Currently I am a Post-doctoral fellow in David Botstein's laboratory at Princeton University.